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Real-time 3D analysis during electron tomography using tomviz

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arxiv 2208.01850 v1 pith:F5DRRZ7V submitted 2022-08-03 cond-mat.mtrl-sci

classification cond-mat.mtrl-sci
keywords tomographyelectronanalysisbiologicalenableinterpretationmaterialminutes
verification ladder T0 review T1 audit T2 compute T3 formal
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The demand for high-throughput electron tomography is rapidly increasing in biological and material sciences. However, this 3D imaging technique is computationally bottlenecked by alignment and reconstruction which runs from hours to days. We demonstrate real-time tomography with dynamic 3D tomographic visualization to enable rapid interpretation of specimen structure immediately as data is collected on an electron microscope. Using geometrically complex chiral nanoparticles, we show volumetric interpretation can begin in less than 10 minutes and a high quality tomogram is available within 30 minutes. Real time tomography is integrated into tomviz, an open source and cross platform 3D analysis tool that contains intuitive graphical user interfaces (GUI) to enable any scientist to characterize biological and material structure in 3D.

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Cited by 1 Pith paper

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  1. NanoMorph-3D: An End-to-End Physics-Driven Unrolling Framework for Nanomaterial Reconstruction

    cs.CV 2026-08 conditional novelty 6.0 of 10

    NanoMorph-3D reconstructs 3D nanomaterial volumes from limited-angle electron tomography using a physics-driven unrolled network with projection-geometry attention, beating iterative and learned baselines on synthetic...

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