REVIEW 4 major objections 6 minor 47 references
ASM-UNet: Adaptive Scan Mamba Integrating Group Commonalities and Individual Variations for Fine-Grained Segmentation
T0 review · 4 major / 6 minor · reviewed 2026-08-05 · deepseek-v4-flash
Pith's one-line read ASM-UNet claims that letting a Mamba-based U-Net choose its scan order per patient—via a group-plus-individual adaptive score—improves fine-grained medical image segmentation, reporting the best average Dice on ACDC (92.61), Synapse (87.27)
desk verdict The BTMS dataset is a real contribution; the adaptive-scan mechanism is plausible but underspecified in the paper, and the empirical margins are thin. read the letter →
The pith
A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.
The reading
What carries the argument
The central object is the adaptive scan score, a per-spatial-location scalar formed as the sum of a group scan score and an individual scan score. The group scan score is a learnable embedding, resized to the spatial dimensions and passed through a sigmoid so its values lie in [0, 1]; it encodes common anatomical layout. The individual scan score is produced by a generator that first scans the patient's features in three fixed directions, mirroring how a clinician builds an initial global impression before looking at small structures. According to the paper, sorting the flattened tokens by the combined adaptive score determines the Mamba scanning order; the score is also concatenated with th
What would settle it
Inspect the released code path that consumes the adaptive scan score: if no permutation or indexing operation reorders the token sequence before the Mamba layers, then the reported Dice gains are not evidence for adaptive scan order. Alternatively, an experiment that replaces the learned ordering with random permutations, while keeping all other components, would show whether reordering itself—rather than extra parameters or the concatenated score—accounts for the improvement.
Extended reading notes
Core claim
The central claim is that the scanning order of a Mamba layer is not a neutral implementation detail: for small, variable anatomical structures, order determines what context the model can assemble, and a fixed horizontal, vertical, or diagonal scan cannot adapt to patients whose ducts join in different patterns. ASM-UNet accordingly replaces the fixed scan with an adaptive scan score at each spatial location. The score is the sum of a group scan score, a learnable embedding normalized by sigmoid that encodes the common layout of the anatomy, and an individual scan score, generated from the patient's own features after three fixed initial scans. Tokens are then reordered according to that sc
Load-bearing premise
The load-bearing premise, asserted in Section IV-B but not demonstrated there, is that sorting the adaptive scan score actually sets the token order fed to Mamba: the text says the score is sorted to determine the order and also says it is concatenated with the feature embedding, but no equation, pseudocode, or diagram shows the conversion from scalar score to permutation.
Editorial extensions
If this is right
- If the adaptive scan score is doing the work, any Mamba-based segmentation model with fixed scan paths could adopt the same dual-score mechanism and should see similar fine-grained gains; the paper positions the mechanism as a replacement for fixed scans.
- On the BTMS dataset, the gap between coarse (76.74) and fine (42.57) Dice shows that distinguishing the eight biliary structures, not just detecting the organ, is where existing methods fail; the paper's reported gains are concentrated there.
- Ablations show the individual scan score and group scan score contribute additively on the hard categories (40.85 to 41.34 to 41.87 to 42.57), so both commonality and variation are needed for the best fine-grained result.
- The hardest classes, CD and RHD, remain below 35% Dice for all methods, so the paper's claim is not that adaptive scanning solves fine-grained segmentation, only that it improves it.
Reading between the lines
- Editorial extension: if the sorting mechanism is real, the learned scan order should be inspectable: visualizing which voxels are processed early versus late in different patients could show whether the order tracks known biliary variants without any extra labeling.
- Editorial extension: the paper compares whole models, so the reported gains could in principle come from other ASM-UNet design details; mounting the same adaptive-score module on an existing fixed-scan Mamba backbone would isolate the contribution of adaptivity.
- Editorial extension: because the only explicit operation involving the score is concatenation, an ablation that forces a true permutation (sort by score, feed reordered tokens) versus one that only concatenates the score would settle whether scan-path adaptivity or feature augmentation causes the Dice gains.
Editorial analysis
A structured set of objections, weighed in public.
Referee Report
Summary. The paper proposes ASM-UNet, a Mamba-based U-Net for 3D medical image segmentation, with the stated goal of improving fine-grained segmentation. The core novelty is an 'adaptive scan score' computed as the sum of a learnable group scan embedding and an image-specific individual scan score; the score is claimed to dynamically determine the token ordering processed by the Mamba layers. The method is evaluated on ACDC, Synapse, and a new BTMS dataset containing eight biliary-tract classes, reporting the highest average Dice on all three datasets. The paper also contributes the BTMS dataset and a GitHub link for code and data.
Significance. If the adaptive-scan mechanism works as described, it addresses a real limitation of Mamba-based segmenters, which typically use fixed scanning paths. The BTMS dataset is potentially a useful benchmark for fine-grained abdominal anatomy. Strengths of the paper include standard held-out evaluation, per-class Dice tables, an ablation study, and a parameter analysis; no definitional circularity is apparent. However, the mechanism that turns the scan score into a permutation is never specified, the key numerical comparisons lack variance estimates, and hyperparameters appear to be selected on test results. These are serious, fixable gaps.
major comments (4)
- [IV-B, Fig. 5, Table V] The central claim is that the adaptive scan score dynamically determines the Mamba scan order. Section IV-B says the scan order is determined by sorting the scores, but the next sentence says the score is concatenated with the feature embedding. No equation, pseudocode, or diagram shows how a scalar score per token is converted into a permutation of the W x H x D sequence; Fig. 5 is titled 'feature reordering' but shows no reordering operation. The ablations in Table V toggle IS/GS only and never remove the sorting while keeping the concatenation, so the gains could come from the added parameters or concatenated features rather than from adaptive scanning. Please specify the exact sorting/inverse operation and add an ablation that isolates the permutation from the score features.
- [V-C, Tables III-IV] All Dice values are from a single run. Several headline margins are under one point (0.55 on ACDC, 0.70 on Synapse, 0.78 on BTMS 'w/ Hard'). Without standard deviations, confidence intervals, or paired significance tests, the claimed superiority over nnFormer and U-Mamba is not established. Report mean +/- std over at least three seeds and, ideally, paired tests or bootstrap intervals.
- [V-E, Table VI, IV-B.1] The default number of Mamba branches appears to be selected on the test set: Table VI reports test Dice for 0-4 branches and the text chooses three branches because it gives the best hard-category score, while four branches are better on non-hard. No validation-based selection is described, and the group scan embedding length n_g is a hyperparameter with no sensitivity analysis. If test data was used for model selection, the reported performance is optimistic. Use a validation split for choosing hyperparameters and report test performance only for the final configuration.
- [III, Table II] BTMS is introduced as a new clinical benchmark, but the paper does not report ethics approval, acquisition details, annotation protocol or inter-observer agreement, inclusion/exclusion criteria, or whether the 4:3:3 split is at case level. These details are necessary for a dataset contribution to be reproducible and clinically credible.
minor comments (6)
- [II-B] References [24] and [37] both call their method Swin-UMamba; clarify the relationship or use distinct labels.
- [Table I] CB is used for gallbladder in Table I, but the rest of the paper and Table II use GB; unify the abbreviation.
- [IV-A] Six encoder blocks are described, but only five downsampling rates and five channel counts are listed; correct the count.
- [Table VI] 0 branches yields the same numbers as M1 in Table V, implying no Mamba at all; clarify what branch count 0 means.
- [IV-B.2] The individual scan score is said to use three fixed scan orders [21]; [21] is the Mamba paper and does not define those orders. Specify the three orders or give a proper reference.
- [Fig. 5] The labels in Figure 5 are too small to read; enlarge them.
Circularity Check
No definitional circularity; adaptive-scan mechanism is under-specified, not circular.
full rationale
ASM-UNet's central claim—adaptive scan scores, formed from group and individual scores, determine the Mamba scan order—is not circular by construction. The group scan score is a learnable embedding, the individual scan score is generated from the patient's features via fixed scans, and both are trained on the training split and evaluated on held-out test folds (ACDC/Synapse/BTMS). No parameter is fitted to the test statistic and then reported as a prediction; all performance numbers come from forward inference on data not used in training. Author self-citations ([5], [20], [23], [38]) appear only in related-work or baseline contexts and do not carry the argument. There is no imported uniqueness theorem and no ansatz smuggled in via citation. The genuine weakness is Section IV-B: the text states 'the scan order is dynamically determined by sorting these scores' but no equation, pseudocode, or figure shows the conversion of the score into a permutation, and the following sentence says the score is 'concatenated with the corresponding feature embedding.' Fig.5 is captioned 'feature reordering' but contains no reordering operation. That is under-specification/verifiability risk—the reported gains could conceivably come from added parameters/concatenation rather than from an actual learned scan path—but it is not circularity, because even if the claimed sorting were implemented exactly as stated, the derivation would not reduce to its inputs. Hyperparameter choices (e.g., three branches) come from validation performance, which is a selection issue rather than a circular derivation. The paper is benchmarked against external methods, and the code/dataset are promised publicly, so the central results are externally checkable. Score 0.
Assumptions & free parameters
free parameters (3)
- Group scan embedding (learnable vector, length n_g) =
learned via gradient descent; n_g hyperparameter not reported
- Individual scan score generator weights =
learned via gradient descent
- Number of Mamba branches =
3 branches used as default; 4 gave higher non-hard Dice
assumptions (4)
- standard math Mamba's selective state space model works as a sequence encoder for flattened image features.
- ad hoc to paper A scalar additive scan score, formed from a learned embedding plus image features, determines a good token ordering for Mamba.
- domain assumption Clinicians initially scan in fixed directions and then dynamically rescan; this analogy motivates the individual scan score design.
- domain assumption BTMS ground-truth labels are anatomically correct and complete.
Cite this review
Pith. "Pith review of ASM-UNet: Adaptive Scan Mamba Integrating Group Commonalities and Individual Variations for Fine-Grained Segmentation." pith.science (2026). https://pith.science/paper/IZWFPJIA
@misc{pith2026250807237,
author = {Pith},
title = {Pith review of: ASM-UNet: Adaptive Scan Mamba Integrating Group Commonalities and Individual Variations for Fine-Grained Segmentation},
year = {2026},
howpublished = {\url{https://pith.science/paper/IZWFPJIA}},
note = {Machine review of arXiv:2508.07237}
}
read the original abstract
Precise lesion resection depends on accurately identifying fine-grained anatomical structures. While many coarse-grained segmentation (CGS) methods have been successful in large-scale segmentation (e.g., organs), they fall short in clinical scenarios requiring fine-grained segmentation (FGS), which remains challenging due to frequent individual variations in small-scale anatomical structures. Although recent Mamba-based models have advanced medical image segmentation, they often rely on fixed manually-defined scanning orders, which limit their adaptability to individual variations in FGS. To address this, we propose ASM-UNet, a novel Mamba-based architecture for FGS. It introduces adaptive scan scores to dynamically guide the scanning order, generated by combining group-level commonalities and individual-level variations. Experiments on two public datasets (ACDC and Synapse) and a newly proposed challenging biliary tract FGS dataset, namely BTMS, demonstrate that ASM-UNet achieves superior performance in both CGS and FGS tasks. Our code and dataset are available at https://github.com/YqunYang/ASM-UNet.
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Reviewed August 5, 2026 · model on record in the stance chip above.
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