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Towards a HIPAA Compliant Agentic AI System in Healthcare

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arxiv 2504.17669 v2 pith:YYWTZMLO submitted 2025-04-24 cs.MA cs.AIcs.ET

classification cs.MAcs.AIcs.ET
keywords agenticcomplianceclinicalframeworkhealthhealthcarehipaaregulatory
verification ladder T0 review T1 audit T2 compute T3 formal
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Agentic AI systems powered by Large Language Models (LLMs) as their foundational reasoning engine, are transforming clinical workflows such as medical report generation and clinical summarization by autonomously analyzing sensitive healthcare data and executing decisions with minimal human oversight. However, their adoption demands strict compliance with regulatory frameworks such as Health Insurance Portability and Accountability Act (HIPAA), particularly when handling Protected Health Information (PHI). This work-in-progress paper introduces a HIPAA-compliant Agentic AI framework that enforces regulatory compliance through dynamic, context-aware policy enforcement. Our framework integrates three core mechanisms: (1) Attribute-Based Access Control (ABAC) for granular PHI governance, (2) a hybrid PHI sanitization pipeline combining regex patterns and BERT-based model to minimize leakage, and (3) immutable audit trails for compliance verification.

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Cited by 2 Pith papers

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score. Full citation record

  1. Agent Security Needs Redefinition through a Holistic Framework

    cs.CR 2026-07 conditional novelty 6.0 of 10

    Agent security should be redefined around four contextual authorization properties instead of the content of the action performed.

  2. Agentic AI framework for End-to-End Medical Data Inference

    cs.AI 2025-07 reject novelty 5.0 of 10

    An unvalidated multi-agent framework is proposed to automate clinical data pipelines from ingestion to inference for tabular and imaging data, with no reported benchmarks.

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