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arxiv: physics/0108016 · v1 · submitted 2001-08-10 · ⚛️ physics.bio-ph · q-bio.GN

Self-organizing Approach for Automated Gene Identification in Whole Genomes

classification ⚛️ physics.bio-ph q-bio.GN
keywords approachbeenfrequenciesgenomesidentificationproposedspacetriplet
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An approach based on using the idea of distinguished coding phase in explicit form for identification of protein-coding regions (exons) in whole genome has been proposed. For several genomes an optimal window length for averaging GC-content function and calculating codon frequencies has been found. Self-training procedure based on clustering in multidimensional space of triplet frequencies is proposed. For visualization of data in the space of triplet requiencies method of elastic maps was applied.

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