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physics.bio-ph

Biological Physics

Molecular biophysics, cellular biophysics, neurological biophysics, membrane biophysics, single-molecule biophysics, ecological biophysics, quantum phenomena in biological systems (quantum biophysics), theoretical biophysics, molecular dynamics/modeling and simulation, game theory, biomechanics, bioinformatics, microorganisms, virology, evolution, biophysical methods.

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Lorentzian family is unique invariant under Riccati transport

Reformulating dynamics on the circle shows the Cauchy law is the sole rotation-invariant measure, unifying exact mean-field reductions.

· “Geometric Origin of Exact Mean-Field Reductions: M{\"o}bius Symmetry and the Lorentzian Ansatz”

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Figure from the paper

Insertion depth drives concentration-dependent bilayer destabilization

Simulations show chloroform thins membranes while alkanols crowd interfaces and redistribute stress without full melting.

· “Concentration-Dependent Membrane Destabilization in DPPC Bilayers: Distinct Insertion Mechanisms and Stress Redistribution by Chloroform and Alkanols”

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Figure from the paper

Flavin vibrations survive electron hop and report the radical anion

10-fs spectroscopy shows low-frequency wave packets mark the first step of cryptochrome photoactivation

· “Coherent vibrational wave packet motion in ErCry4a proteins monitors the redox state of the flavin chromophore”

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1 mm mid-infrared chemical imaging via high-energy OPO

A commercial OPO delivering 360 µJ pulses breaks the field-of-view barrier in wide-field photothermal microscopy, enabling millimeter-scale,

· “Millimeter-scale wide-field mid-infrared photothermal imaging enabled by a broadly tunable picosecond optical parametric oscillator”

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Figure from the paper

Last boundary hit, not barrier top, defines reactant states

Flux, correlation and relaxation then agree and recover Kramers’ rates for high barriers.

· “Modern view of activated rate processes: unidirectional fluxes at equilibrium, correlation functions, and splitting probabilities”

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Figure from the paper

H2O2 alone sends diatom biofilms diving into sediment

Oxidative stress triggers rapid downward migration even in darkness, separate from the usual light-protection cycle

· “Reactive oxygen species trigger downward vertical migration in diatom microphytobenthic biofilms as a strategy to cope with oxidative stress”

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Figure from the paper

Grey-matter phantoms grown from real cell shapes for MRI

ConCeG packs neurons and glia into dense digital tissue so diffusion signals can be simulated with known ground truth

· “Contextual Cellular Growth (ConCeG) of neural cells for realistic grey matter tissue generation for diffusion MRI simulations”

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Figure from the paper

Gliding mammal wing shapes trade lift for control authority

CFD tests of different patagia and tails find each excels at distinct tasks rather than converging on one optimum.

· “Patagium and tail morphology shape aerodynamic performance and control authority in gliding-mammal-inspired wings”

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Figure from the paper

Point source restores identifiability of spatial dynamics from snapshots

Distributed sources cannot be uniquely recovered from static patterns, but a transcription site allows physics-informed methods to infer the

· “Identifiability Limits of Physics-Informed Inference for Spatial Stochastic Dynamics from Static Snapshots”

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Figure from the paper

Clathrin coats develop stiffness and memory from growth conditions

Simulations reveal how emergent properties create two gates that decide flat, stalled or closed fates and match experiments without fitting.

· “Pathway variability, coat stiffening and mechanical adaptation during clathrin-mediated endocytosis”

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Anchored magnetic bot chains buckle into sustained flagellar beating

Stress from self-propulsion overcomes dipole stiffness, producing Hopf-bifurcation oscillations in macroscopic chains.

· “Emergence of beating in a magnetic flagellum consisting of active bots”

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Bacterial flows order independently of cell polarity

Near-field interactions break the force-dipole alignment, so total active forcing no longer follows cell direction and mobility increases un

· “Flow-polarity decoupling and universal mobility enhancement in dense bacterial active fluids with mesoscale order”

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Figure from the paper

ILTS-SINDy recovers nonlinear dynamics models from data with up to 20% outliers by first…

ILTS-SINDy decouples outlier detection from sparse regression and maintains accuracy with up to 20% corrupted observations.

· “Robust Sparse Identification of Nonlinear Dynamics via Least Trimmed Squares”

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Optimal transport fits exact master equations to discrete data

Maximum-likelihood estimators enable memory-inclusive models without Markov or equilibrium assumptions for biomolecular kinetics.

· “Optimal parameterization of nonequilibrium generalized master equations from discrete-time experimental data”

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Figure from the paper

NanoVer brings live MD simulations into shared XR on commodity headsets

Multiple users on standalone hardware can now treat flexible molecules as tangible objects during real-time simulations.

· “NanoVer: An open-source framework for interactive molecular dynamics in extended reality (iMD-XR) on commodity hardware”

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Figure from the paper

Fusion and recovery of droplets obey separate mechanisms

Fusion proceeds via localized neck growth and bridge expansion while recovery follows global exponential decay; viscoelasticity adds a disti

· “Droplet Fusion as a Relaxation Process: Comparison with Shape Recovery of Newtonian and Viscoelastic Droplets”

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Figure from the paper

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