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Shape Changes of Self-Assembled Actin Bilayer Composite Membranes

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arxiv physics/9712020 v1 pith:AIGRBZFX submitted 1997-12-12 physics.bio-ph q-bio

classification physics.bio-phq-bio
keywords actinbilayervesiclescortexmembranesanalysisbeneathblisters
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We report the self-assembly of thin actin shells beneath the membranes of giant vesicles. Ion-carrier mediated influx of Mg2+ induces actin polymerization in the initially spherical vesicles. Buckling of the vesicles and the formation of blisters after thermally induced bilayer expansion is demonstrated. Bilayer flickering is dominated by tension generated by its coupling to the actin cortex. Quantitative flicker analysis suggests the bilayer and the actin cortex are separated by 0.4 \mum to 0.5 \mum due to undulation forces.

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