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Ultraconserved Sequences in the Honeybee Genome - Are GC-rich Regions Preferred?

Genomics · Submitted 18 Feb 2007

abstract compiled · 2026-09-23 · no language-model review

The authors' main claim They showed strong preferences towards locating in the GC-rich regions of the bee genome.

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arXiv IDq-bio/0702037 (version 1)
Pith IDJQPPM4AR, Pith's permanent record of this paper and its review
CitationManoj Pratim Samanta. "Ultraconserved Sequences in the Honeybee Genome - Are GC-rich Regions Preferred?." arXiv:q-bio/0702037 (2007). https://pith.science/paper/JQPPM4AR
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What the abstract itself states, as probabilities: claims first 0.05 · states limitation 0.10 · human participants 0.01 · controlled comparison 0.22 · randomized assignment 0.01 · states quantitative result 0.77 · compares with prior results 0.51 · mentions code or data availability 0.02.

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arXiv listing abstract v1. Results and the main claim are underlined; .

Among all insect genomes, honeybee displays one of the most unusual patterns with interspersed long AT and GC-rich segments. Nearly 75% of the protein-coding genes are located in the AT-rich segments of the genome, but the biological significance of the GC-rich regions is not well understood. Based on an observation that the bee miRNAs, actins and tubulins are located in the GC-rich segments, this work investigated whether other highly conserved genomic regions show similar preferences. Sequences ultraconserved between the genomes of honeybee and Nasonia, another hymenopteran insect, were determined. They showed strong preferences towards locating in the GC-rich regions of the bee genome.

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#sentencerolethe authors' own workstates the main conclusionstrength
s0 Among all insect genomes, honeybee displays one of the most unusual patterns with interspersed long AT and GC-rich segments. background 1.00 0.10 0.02 asserted 0.99
s1 Nearly 75% of the protein-coding genes are located in the AT-rich segments of the genome, but the biological significance of the GC-rich regions is not well understood. gap 0.70 0.15 0.03 asserted 1.00
s2 Based on an observation that the bee miRNAs, actins and tubulins are located in the GC-rich segments, this work investigated whether other highly conserved genomic regions show similar preferences. contribution 0.88 0.56 0.03 asserted 0.63
s3 Sequences ultraconserved between the genomes of honeybee and Nasonia, another hymenopteran insect, were determined. method 0.90 0.91 0.02 asserted 0.95
s4 They showed strong preferences towards locating in the GC-rich regions of the bee genome. result 1.00 0.88 0.87 asserted 1.00

What kind of paper the classifier reports this is: empirical study 0.99 · evidence from analysis of existing data 0.81.

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Every quoted sentence on this record is the authors'. Every label is from Pith's closed vocabulary, with the probability shown beside it. Every number in the measurements table is the authors', checked by code. Record as JSON

The paper
Original abstract

Among all insect genomes, honeybee displays one of the most unusual patterns with interspersed long AT and GC-rich segments. Nearly 75% of the protein-coding genes are located in the AT-rich segments of the genome, but the biological significance of the GC-rich regions is not well understood. Based on an observation that the bee miRNAs, actins and tubulins are located in the GC-rich segments, this work investigated whether other highly conserved genomic regions show similar preferences. Sequences ultraconserved between the genomes of honeybee and Nasonia, another hymenopteran insect, were determined. They showed strong preferences towards locating in the GC-rich regions of the bee genome.

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