Is the Universe a Quantum System?

In order to relate the probabilistic predictions of quantum theory uniquely to measurement results, one has to conceive of an ensemble of identically prepared copies of the quantum system under study. Since the universe is the total domain of physical experience, it cannot be copied, not even in a thought experiment. Therefore, a quantum state of the whole universe can never be made accessible to empirical test. Hence the existence of such a state is only a metaphysical idea. Despite prominent claims to the contrary, recent developments in the quantum-interpretation debate do not invalidate this conclusion.