The beta-neurexin/neuroligin-1 interneuronal intrasynaptic adhesion is essential for quantum brain dynamics

There are many blank areas in understanding the brain dynamics and especially how it gives rise to consciousness. Quantum mechanics is believed to be capable of explaining the enigma of conscious experience, however till now there is not good enough model considering both the data from clinical neurology and having some explanatory power. In this paper is presented a novel model in defence of macroscopic quantum events within and between neural cells. The synaptic beta-neurexin/neuroligin-1 adhesive protein complex is claimed to be not just the core of the excitatory glutamatergic CNS synapse, instead it is a device mediating entanglement between the cytoskeletons of the cortical neurons. Thus the macroscopic coherent quantum state can extend throughout large brain cortical areas and the subsequent collapse of the wavefunction could affect simultaneously the subneuronal events in millions of neurons. The neuroligin-1/beta-neurexin/synaptotagmin-1 complex also controls the process of exocytosis and provides an interesting and simple mechanism for retrograde signalling during learning-dependent changes in synaptic connectivity. A brief outlook of the molecular machinery driving neuromediator release through exocytosis is provided with particular emphasis on the possibility for vibrationally-assisted tunneling.