Pith Number

pith:AXMGWEF6

pith:2026:AXMGWEF6TA6BLI27ESJCYRIAOS

not attested not anchored not stored refs resolved

Modeling Optical Polarization Evolution in Myelinated Axon Waveguides with Realistic Imperfections

Christoph Simon, Ethan Davies, Rishabh

Realistic imperfections in myelinated axons reduce polarization fidelity but permit recoveries reaching 0.8 in certain modes.

arxiv:2605.15211 v1 · 2026-05-07 · physics.bio-ph

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\pithnumber{AXMGWEF6TA6BLI27ESJCYRIAOS}

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Record completeness

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2 Internet Archive

3 Author claim open · sign in to claim

4 Citations open

5 Replications open

✓ Portable graph bundle live · download bundle · merged state

The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Claims

C1strongest claim

When all imperfections are combined in a single axon model, the simulations show substantial drops in fidelity, yet certain modes exhibit recovery, with repeated revivals reaching values of around 0.8, which exceeds the revivals observed in the single imperfection cases.

C2weakest assumption

The computational waveguide model with four nodes of Ranvier and the three specified structural imperfections (myelin thickness variation, non-circular cross-section, axonal bending) sufficiently represents the optical polarization evolution that would occur in actual in vivo myelinated axons.

C3one line summary

Simulations of myelinated axons with myelin thickness variation, non-circular cross-sections, and bending show polarization fidelity drops but recovers to ~0.8 in certain modes when all imperfections combine.

References

85 extracted · 85 resolved · 0 Pith anchors

[1] McKilliam, Explanation, understanding, and the methodological problem in consciousness science, Syn- these205, 142 (2025) 2025

[2] C. Koch, M. Massimini, M. Boly, and G. Tononi, Neural correlates of consciousness: progress and problems, Nat. Rev. Neurosci.17, 307 (2016) 2016

[3] N. P. Franks, General anaesthesia: from molecular tar- gets to neuronal pathways of sleep and arousal, Nat. Rev. Neurosci.9, 370 (2008). 8 2008

[4] G. A. Mashour, Integrating the science of consciousness and anesthesia, Anesth. Analg.103, 975 (2006) 2006

[5] Y. Humeau and D. Choquet, The next generation of ap- proaches to investigate the link between synaptic plastic- ity and learning, Nat. Neurosci.22, 1536 (2019) 2019

Formal links

2 machine-checked theorem links

Receipt and verification

First computed	2026-05-20T00:00:46.414674Z
Builder	pith-number-builder-2026-05-17-v1
Signature	Pith Ed25519 (`pith-v1-2026-05`) · public key
Schema	pith-number/v1.0

Canonical hash

05d86b10be983c15a35f24922c45007496d214d63b2c15ab9b7a3a6576af34c3

Aliases

arxiv: 2605.15211 · arxiv_version: 2605.15211v1 · doi: 10.48550/arxiv.2605.15211 · pith_short_12: AXMGWEF6TA6B · pith_short_16: AXMGWEF6TA6BLI27 · pith_short_8: AXMGWEF6

Agent API

Resolver JSON Graph JSON Events JSON Schema Signing key

Verify this Pith Number yourself

curl -sH 'Accept: application/ld+json' https://pith.science/pith/AXMGWEF6TA6BLI27ESJCYRIAOS \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 05d86b10be983c15a35f24922c45007496d214d63b2c15ab9b7a3a6576af34c3

Canonical record JSON

{
  "metadata": {
    "abstract_canon_sha256": "4efb79d82b2bd3c9a9cebffe596eda6d68d84f40bc7d00d7a1968d3fa1921f3f",
    "cross_cats_sorted": [],
    "license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
    "primary_cat": "physics.bio-ph",
    "submitted_at": "2026-05-07T20:09:57Z",
    "title_canon_sha256": "eb39b678aaee3cfc1c4501bf62d25df5b0d9be498ad097a8319e85051fafd536"
  },
  "schema_version": "1.0",
  "source": {
    "id": "2605.15211",
    "kind": "arxiv",
    "version": 1
  }
}