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Medagentsbench: Benchmarking thinking models and agent frameworks for complex medical reasoning

11 Pith papers cite this work, alongside 2 external citations. Polarity classification is still indexing.

11 Pith papers citing it
2 external citations · Pith
abstract

Complex medical reasoning requires integrating heterogeneous clinical evidence across multiple inference steps. Large language models (LLMs) now approach this through two routes: internalized reasoning and externalized agent scaffolding (frameworks that decompose problems collaboratively amongst multiple LLMs). To determine whether these routes are exclusive or complementary, we introduce MedicalAgentsBench, a filtered benchmark of 862 complex clinical questions drawn from the union of eight medical datasets via difficulty-aware curation and contamination screening. Evaluating three internalized reasoning models (DeepSeek-R1, o1-mini, and o3-mini), seven base models, and nine externalized agent-based methods, we find that internalized and externalized approaches each independently improve performance, and that their benefits compound: the highest accuracy is achieved by layering agent workflows onto an internalized reasoning model (i.e., o3-mini + MDAgents with 35.1%). Pareto analysis shows this combination dominates the cost-performance frontier; moreover, lightweight optimization on inexpensive models offers an entry point for resource-constrained settings. Our benchmark is at https://github.com/gersteinlab/MedicalAgentsBench.

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background 1 baseline 1 dataset 1

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years

2026 7 2025 4

representative citing papers

Multimodal Chain-of-Thought Reasoning: A Comprehensive Survey

cs.CV · 2025-03-16 · unverdicted · novelty 2.0

The paper provides the first comprehensive survey of multimodal chain-of-thought reasoning, including foundational concepts, a taxonomy of methodologies, application analyses, challenges, and future directions.

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Showing 11 of 11 citing papers.