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arxiv: 1007.5022 · v1 · submitted 2010-07-28 · 🧬 q-bio.NC · cond-mat.dis-nn· physics.bio-ph

Percolation in living neural networks

classification 🧬 q-bio.NC cond-mat.dis-nnphysics.bio-ph
keywords neuralconnectivitylivingnetworksneuronspercolationapproachbalance
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We study living neural networks by measuring the neurons' response to a global electrical stimulation. Neural connectivity is lowered by reducing the synaptic strength, chemically blocking neurotransmitter receptors. We use a graph-theoretic approach to show that the connectivity undergoes a percolation transition. This occurs as the giant component disintegrates, characterized by a power law with critical exponent $\beta \simeq 0.65$ is independent of the balance between excitatory and inhibitory neurons and indicates that the degree distribution is gaussian rather than scale free

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