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arxiv: 1306.4602 · v1 · pith:KMZ6LIU4new · submitted 2013-06-19 · ⚛️ physics.bio-ph · cond-mat.soft· q-bio.BM

Electrophoresis of a DNA Coil Near a Nanopore

classification ⚛️ physics.bio-ph cond-mat.softq-bio.BM
keywords fieldpolymercoilelectrophoresislongnanoporeneararound
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Motivated by DNA electrophoresis near a nanopore, we consider the flow field around an "elongated jet", a long thin source which injects momentum into a liquid. This solution qualitatively describes the electro-osmotic flow around a long rigid polymer, where due to electrohydrodynamic coupling, the solvent receives momentum from the electric field. Based on the qualitative behavior of the elongated jet solution, we develop a coarse-grained scheme which reproduces the known theoretical results regarding the electrophoretic behavior of a long rigid polymer and a polymer coil in a uniform field, which we then exploit to analyze the electrophoresis of a polymer coil in the non-uniform field near a nanopore.

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