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arxiv: cond-mat/0010130 · v2 · submitted 2000-10-09 · ❄️ cond-mat.soft · cond-mat.stat-mech· q-bio

Dynamic concentration of motors in microtubule arrays

classification ❄️ cond-mat.soft cond-mat.stat-mechq-bio
keywords motorsarraysastersconcentrationmicrotubuletheoreticaltwo-dimensionalartificial
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We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.

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