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arxiv: cond-mat/0303468 · v1 · submitted 2003-03-21 · ❄️ cond-mat.stat-mech · physics.bio-ph· q-bio.CB

Percolation, Morphogenesis, and Burgers Dynamics in Blood Vessels Formation

classification ❄️ cond-mat.stat-mech physics.bio-phq-bio.CB
keywords behaviorbloodformationmodelpercolationsystemvesselsaggregates
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Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological system. We show that both the model and the real system exhibit a fractal behavior at small scales, due to the process of migration and dynamical aggregation, followed at large scale by a random percolation behavior due to the coalescence of aggregates. The results are in good agreement with the analysis performed on the experimental data.

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