pith. sign in

arxiv: physics/0303120 · v1 · submitted 2003-03-28 · ⚛️ physics.bio-ph · cond-mat.stat-mech· q-bio.PE

Analytical study of the effect of recombination on evolution via DNA shuffling

classification ⚛️ physics.bio-ph cond-mat.stat-mechq-bio.PE
keywords modelanalyticalevolutionpopulationrecombinationshufflingallowsapplied
0
0 comments X
read the original abstract

We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selection, recombination and point mutations. The simplicity of the model allows us to obtain a full analytical treatment of both its dynamical and equilibrium properties, for the case of an infinite population. We also briefly discuss finite population size corrections.

This paper has not been read by Pith yet.

discussion (0)

Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.