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This Patient Looks Like That Patient: Prototypical Networks for Interpretable Diagnosis Prediction from Clinical Text

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arxiv 2210.08500 v1 pith:VYW36DTP submitted 2022-10-16 cs.CL

This Patient Looks Like That Patient: Prototypical Networks for Interpretable Diagnosis Prediction from Clinical Text

classification cs.CL
keywords clinicaldoctorsprototypicaltextdiagnosisinterpretablemodelmodels
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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The use of deep neural models for diagnosis prediction from clinical text has shown promising results. However, in clinical practice such models must not only be accurate, but provide doctors with interpretable and helpful results. We introduce ProtoPatient, a novel method based on prototypical networks and label-wise attention with both of these abilities. ProtoPatient makes predictions based on parts of the text that are similar to prototypical patients - providing justifications that doctors understand. We evaluate the model on two publicly available clinical datasets and show that it outperforms existing baselines. Quantitative and qualitative evaluations with medical doctors further demonstrate that the model provides valuable explanations for clinical decision support.

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  1. Structured Information Matters: Explainable ICD Coding with Patient-Level Knowledge Graphs

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    Integrating patient-level knowledge graphs into the PLM-ICD model improves ICD-9 coding Macro-F1 by up to 3.2% on MIMIC-III while adding explainability.