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ECG Semantic Integrator (ESI): A Foundation ECG Model Pretrained with LLM-Enhanced Cardiological Text

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arxiv 2405.19366 v2 pith:M5CG3MNK submitted 2024-05-26 eess.SP cs.AI

classification eess.SPcs.AI
keywords learningbaselinescontrastivedeepframeworkincludingintegratesintegrator
verification ladder T0 review T1 audit T2 compute T3 formal
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The utilization of deep learning on electrocardiogram (ECG) analysis has brought the advanced accuracy and efficiency of cardiac healthcare diagnostics. By leveraging the capabilities of deep learning in semantic understanding, especially in feature extraction and representation learning, this study introduces a new multimodal contrastive pretaining framework that aims to improve the quality and robustness of learned representations of 12-lead ECG signals. Our framework comprises two key components, including Cardio Query Assistant (CQA) and ECG Semantics Integrator(ESI). CQA integrates a retrieval-augmented generation (RAG) pipeline to leverage large language models (LLMs) and external medical knowledge to generate detailed textual descriptions of ECGs. The generated text is enriched with information about demographics and waveform patterns. ESI integrates both contrastive and captioning loss to pretrain ECG encoders for enhanced representations. We validate our approach through various downstream tasks, including arrhythmia detection and ECG-based subject identification. Our experimental results demonstrate substantial improvements over strong baselines in these tasks. These baselines encompass supervised and self-supervised learning methods, as well as prior multimodal pretraining approaches.

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Cited by 5 Pith papers

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score.

  1. PRISM-CTG: A Foundation Model for Cardiotocography Analysis with Multi-View SSL

    cs.LG 2026-04 unverdicted novelty 6.0 of 10

    PRISM-CTG is the first large-scale foundation model for cardiotocography that uses multi-view self-supervised learning on unlabeled data to learn transferable representations, outperforming baselines on seven downstre...

  2. HeartcareGPT: A Unified Multimodal ECG Suite for Dual Signal-Image Modeling and Understanding

    cs.LG 2025-06 unverdicted novelty 6.0 of 10

    HeartcareGPT proposes Dual Stream Projection Alignment (DSPA) on a structure-aware tokenizer for unified ECG signal-image modeling, supported by Heartcare-400K dataset and Heartcare-Bench.

  3. EchoBridge: Long-Tail-Aware ECG-Echocardiography Text Alignment for Echocardiography-Derived Cardiac Findings

    cs.LG 2026-07 conditional novelty 5.5 of 10

    EchoBridge’s shared–private ECG–echo-text alignment plus frequency-adaptive prototypes beats strong baselines on classifier-free and cross-center frozen probing, including several low-prevalence valvular findings.

  4. Physiology-Aware CNN and Zero-Shot Multimodal LLMs for ECG Image Classification: A Comparative Study

    cs.LG 2026-06 unverdicted novelty 4.0 of 10

    Zero-shot LLMs achieve near-chance ROC-AUC (~0.5) on ECG image classification while CNN models reach 0.92-0.94 internally and 0.85-0.86 externally on PTB-XL.

  5. ECG Foundation Models and Medical LLMs for Agentic Cardiovascular Intelligence at the Edge: A Review and Outlook

    eess.SP 2026-04 unverdicted novelty 3.0 of 10

    ECG foundation models for signal interpretation and medical LLMs for reasoning can be integrated into agentic systems for real-time cardiovascular intelligence on edge devices.

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