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arxiv 1910.13042 v2 pith:3CCENS7V submitted 2019-10-29 eess.IV cs.CV

Deep Multi-Magnification Networks for Multi-Class Breast Cancer Image Segmentation

classification eess.IV cs.CV
keywords breastanalysiscancerdeepexcisionmulti-classmulti-magnificationpathologists
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing histologic slides prepared from formalin-fixed tissue. In this paper, we present Deep Multi-Magnification Network trained by partial annotation for automated multi-class tissue segmentation by a set of patches from multiple magnifications in digitized whole slide images. Our proposed architecture with multi-encoder, multi-decoder, and multi-concatenation outperforms other single and multi-magnification-based architectures by achieving the highest mean intersection-over-union, and can be used to facilitate pathologists' assessments of breast cancer.

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