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arxiv 2504.17739 v1 pith:4DGTMPUB submitted 2025-04-24 cs.LG

Interpretable Early Detection of Parkinson's Disease through Speech Analysis

classification cs.LG
keywords speechapproachparkinsondetectiondiseaseimpairmentsprovidingearly
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning advances providing promising tools for timely detection. In this research, we propose a deep learning approach for early Parkinson's disease detection from speech recordings, which also highlights the vocal segments driving predictions to enhance interpretability. This approach seeks to associate predictive speech patterns with articulatory features, providing a basis for interpreting underlying neuromuscular impairments. We evaluated our approach using the Italian Parkinson's Voice and Speech Database, containing 831 audio recordings from 65 participants, including both healthy individuals and patients. Our approach showed competitive classification performance compared to state-of-the-art methods, while providing enhanced interpretability by identifying key speech features influencing predictions.

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