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We report the first detection of variability in the mid-infrared neon line emission of a protoplanetary disk by comparing a JWST MIRI MRS spectrum of SZ Cha taken in 2023 with a Spitzer IRS SH spectrum of this object from 2008. We measure the [Ne III]-to-[Ne II] line flux ratio, which is a diagnostic of the high-energy radiation field, to distinguish between the dominance of EUV- or X-ray-driven disk photoevaporation. We find that the [Ne III]-to-[Ne II] line flux ratio changes significantly from $\sim1.4$ in 2008 to $\sim0.2$ in 2023. This points to a switch from EUV-dominated to X-ray-dominated photoevaporation of the disk. We present contemporaneous ground-based optical spectra of the Halpha emission line that show the presence of a strong wind in 2023. We propose that this strong wind prevents EUV radiation from reaching the disk surface while the X-rays permeate the wind and irradiate the disk. We speculate that at the time of the Spitzer observations, the wind was suppressed and EUV radiation reached the disk. These observations confirm that the MIR neon emission lines are sensitive to changes in high-energy radiation reaching the disk surface. This highlights the [Ne III]-to-[Ne II] line flux ratio as a tool to gauge the efficiency of disk photoevaporation in order to provide constraints on the planet-formation timescale. However, multiwavelength observations are crucial to interpret the observations and properly consider the star-disk connection.