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Dynamic and thermodynamic bounds for collective motor-driven transport

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arxiv 2202.13992 v2 pith:I5BLCWNW submitted 2022-02-28 cond-mat.stat-mech q-bio.QM

Dynamic and thermodynamic bounds for collective motor-driven transport

classification cond-mat.stat-mech q-bio.QM
keywords motorstransportboundscargofrontiersparetosystemsanalytic
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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Molecular motors work collectively to transport cargo within cells, with anywhere from one to several hundred motors towing a single cargo. For a broad class of collective-transport systems, we use tools from stochastic thermodynamics to derive a new lower bound for the entropy production rate which is tighter than the second law. This implies new bounds on the velocity, efficiency, and precision of general transport systems and a set of analytic Pareto frontiers for identical motors. In a specific model, we identify conditions for saturation of these Pareto frontiers.

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