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Radiomic biomarker extracted from PI-RADS 3 patients support more e\`icient and robust prostate cancer diagnosis: a multi-center study

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arxiv 2112.13686 v1 pith:RSOBJN7U submitted 2021-12-23 eess.IV cs.CVphysics.med-ph

Radiomic biomarker extracted from PI-RADS 3 patients support more e\`icient and robust prostate cancer diagnosis: a multi-center study

classification eess.IV cs.CVphysics.med-ph
keywords biomarkerspi-radsdatadiagnosispatientsprostateachievecancer
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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Prostate Imaging Reporting and Data System (PI-RADS) based on multi-parametric MRI classi\^ees patients into 5 categories (PI-RADS 1-5) for routine clinical diagnosis guidance. However, there is no consensus on whether PI-RADS 3 patients should go through biopsies. Mining features from these hard samples (HS) is meaningful for physicians to achieve accurate diagnoses. Currently, the mining of HS biomarkers is insu\`icient, and the e\'eectiveness and robustness of HS biomarkers for prostate cancer diagnosis have not been explored. In this study, biomarkers from di\'eerent data distributions are constructed. Results show that HS biomarkers can achieve better performances in di\'eerent data distributions.

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