Not yet reviewed by Pith; the record is open.

We present a new model of interstellar dust in which large grains are a single composite material, ``astrodust,'' and nanoparticle-sized grains come in distinct varieties including polycyclic aromatic hydrocarbons (PAHs). We argue that a single-composition model for grains larger than $\sim$0.02 $\mu$m most naturally explains the lack of frequency dependence in the far-infrared (FIR) polarization fraction and the characteristic ratio of optical to FIR polarization. We derive a size distribution and alignment function for 1.4:1 oblate astrodust grains that, with PAHs, reproduce the mean wavelength dependence and polarization of Galactic extinction and emission from the diffuse interstellar medium while respecting constraints on solid phase abundances. All model data and Python-based interfaces are made publicly available.