Multi-messenger connection in high-energy neutrino astronomy

Low fluxes of astrophysical neutrinos at TeV energies and the overwhelming background of atmospheric neutrinos below that, render the current paradigm of neutrino astronomy as a severely statistics limited one. While many hints have emerged, all the evidence gathered by IceCube and ANTARES, over the course of almost a decade and a half of operation, have fallen short of providing any conclusive answer to the puzzle of the origin of high-energy cosmic rays and neutrinos. The advancement of the field is thus closely associated with not only the neutrino observatories coming online in the next few years, but also on the coordinated efforts of the EM, GW and cosmic ray communities to develop dedicated channels and infrastructure that allows for swift and comprehensive multi-messenger follow-up of relevant events detected in any of the sectors. This paper highlights the strides that have been already taken in that direction and the fruits that they have born, as well as the challenges that lie ahead.