Percolation, Morphogenesis, and Burgers Dynamics in Blood Vessels Formation
classification
❄️ cond-mat.stat-mech
physics.bio-phq-bio.CB
keywords
behaviorbloodformationmodelpercolationsystemvesselsaggregates
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Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological system. We show that both the model and the real system exhibit a fractal behavior at small scales, due to the process of migration and dynamical aggregation, followed at large scale by a random percolation behavior due to the coalescence of aggregates. The results are in good agreement with the analysis performed on the experimental data.
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