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arxiv: cond-mat/9904421 · v1 · submitted 1999-04-29 · ❄️ cond-mat.soft · cond-mat.stat-mech· q-bio

Simple models of proteins with repulsive non-native contacts

classification ❄️ cond-mat.soft cond-mat.stat-mechq-bio
keywords non-nativerepulsivecontactcontactsenergiesenergyfoldingattractive
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The Go model is extended to the case when the non-native contact energies may be either attractive or repulsive. The folding temperature is found to increase with the energy of non-native contacts. The repulsive non-native contact energies may lead to folding at T=0 for some two-dimensional sequences and to reduction in complexity of disconnectivity graphs for local energy minima.

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