A one-step flow matching model using transformer in VAE latent space with non-Gaussian source and auxiliary networks generates accurate high-resolution path-dependent stress fields, achieving 6-7x CPU and ~100x GPU speedup over FEM.
Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager
3 Pith papers cite this work. Polarity classification is still indexing.
3
Pith papers citing it
representative citing papers
A coupled LSTM-GNN model reconstructs local elasto-plastic stress fields from macroscopic loading paths on a plate-with-hole microstructure, achieving 1000x speedup and mesh transferability with 1.9% error.
A delay integro-differential equation model fitted to pharmacokinetic and RNA-seq data indicates that a single medium-to-high dose of pembrolizumab may suffice for effective neoadjuvant eradication of locally advanced MSI-H/dMMR colorectal tumors.
citing papers explorer
-
Optimisation of neoadjuvant pembrolizumab therapy for locally advanced MSI-H/dMMR colorectal cancer using data-driven delay integro-differential equations
A delay integro-differential equation model fitted to pharmacokinetic and RNA-seq data indicates that a single medium-to-high dose of pembrolizumab may suffice for effective neoadjuvant eradication of locally advanced MSI-H/dMMR colorectal tumors.