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arxiv: 1405.3946 · v1 · pith:NKCJ6LQ3new · submitted 2014-05-13 · 🧬 q-bio.QM · cond-mat.mes-hall· cond-mat.mtrl-sci· physics.chem-ph

Silicene-based DNA Nucleobase Sensing

classification 🧬 q-bio.QM cond-mat.mes-hallcond-mat.mtrl-sciphysics.chem-ph
keywords nucleobaseselectricalorientationspresencepropertiesabsenceanalyzebases
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We propose a DNA sequencing scheme based on silicene nanopores. Using first principles theory, we compute the electrical properties of such pores in the absence and presence of nucleobases. Within a two-terminal geometry, we analyze the current-voltage relation in the presence of nucleobases with various orientations. We demonstrate that when nucleobases pass through a pore, even after sampling over many orientations, changes in the electrical properties of the ribbon can be used to discriminate between bases.

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