Nucleon and hadron structure changes in the nuclear medium and impact on observables

We review the effect of hadron structure changes in a nuclear medium using the quark-meson coupling (QMC) model, which is based on a mean field description of non-overlapping nucleon (or baryon) bags bound by the self-consistent exchange of scalar and vector mesons. This approach leads to simple scaling relations for the changes of hadron masses in a nuclear medium. It can also be extended to describe finite nuclei, as well as the properties of hypernuclei and meson-nucleus deeply bound states. It is of great interest that the model predicts a variation of the nucleon form factors in nuclear matter. We also study the empirically observed, Bloom-Gilman (quark-hadron) duality. Other applications of the model include subthreshold kaon production in heavy ion collisions, D and D-bar meson production in antiproton-nucleus collisions, and J/Psi suppression. In particular, the modification of the D and D-bar meson properties in nuclear medium can lead to a large J/Psi absorption cross section, which explains the observed J/Psi suppression in relativistic heavy ion collisions.