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Exact Distributions of Currents and Frenesy for Markov Bridges
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We consider discrete-time Markov bridges, chains whose initial and final states coincide. We derive exact finite-time formulae for the joint probability distributions of additive functionals of trajectories. We apply our theory to time-integrated currents and frenesy of enzymatic reactions, which may include absolutely irreversible transitions. We discuss the information that frenesy carries about the currents and show that bridges may violate known uncertainty relations in certain cases. Numerical simulations are in perfect agreement with our theory.
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