Not yet reviewed by Pith; the record is open.

Background: Charge-exchange reactions are a powerful tool for exploring nuclear structure and nuclear astrophysics, however, a robust charge-exchange reaction theory with quantified uncertainties is essential to extracting reliable physics. Purpose: The goal of this work is to determine the uncertainties due to optical potentials used in the theory for charge-exchange reactions to isobaric analogue states. Method: We implement a two-body reaction model to study (p,n) charge-exchange transitions and perform a Bayesian analysis. We study the (p,n) reaction to the isobaric analog states of $^{14}$C, $^{48}$Ca, and $^{90}$Zr targets over a range of beam energies. We compare predictions using standard phenomenological optical potentials with those obtained microscopically. Results: Charge-exchange cross sections are reasonably reproduced by modern optical potentials. However, when uncertainties in the optical potentials are accounted for, the resulting predictions of charge-exchange cross sections have very large uncertainties. Conclusions: The charge-exchange reaction cross section is strongly sensitive to the input interactions, making it a good candidate to further constrain nuclear forces and aspects of bulk nuclear matter. However, further constraints on the optical potentials are necessary for a robust connection between this tool and the underlying isovector properties of nuclei.