Psychological and behavioural responses in human-agent vs. human-human interactions: a systematic review and meta-analysis
Pith reviewed 2026-05-18 13:34 UTC · model grok-4.3
The pith
Humans display less prosocial behavior and moral engagement with agents than with other humans in similar interactions.
A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.
Core claim
The meta-analysis shows that individuals exhibit less prosocial behaviour and moral engagement when interacting with agents versus humans. They attribute less agency and responsibility to agents, perceiving them as less competent, likeable, and socially present. In contrast, social alignment, trust, personal agency, task performance, and interaction experiences are generally comparable. High heterogeneity in subjective responses indicates context-dependency, with moderators identified in study and participant characteristics.
What carries the argument
A systematic review and meta-analysis integrating 468 effect sizes from 146 studies on partner effects in matched dyadic interactions.
If this is right
- Functional behaviors like task performance remain similar regardless of whether the partner is an agent or human.
- Social attributions such as perceived agency and responsibility are lower for agents.
- Prosocial and moral responses are reduced in human-agent interactions.
- Interaction experiences and trust levels show comparability but with high variability depending on context.
Where Pith is reading between the lines
- Agent designers might prioritize features that enhance perceived social presence to increase moral engagement.
- This distinction could influence ethical guidelines for deploying agents in roles involving care or decision support.
- Long-term exposure to agents might change these attributions over time in ways not captured by current studies.
Load-bearing premise
The included studies allow for meaningful comparison and pooling of effects despite variations in interaction scenarios, populations, and measures.
What would settle it
A large-scale study using identical interaction tasks and measures for both agent and human partners that finds no difference in prosocial behavior would falsify the central pattern of reduced moral engagement with agents.
Figures
read the original abstract
Interactive intelligent agents are being integrated across society. Despite achieving human-like capabilities, humans' responses to these agents remain poorly understood, with research fragmented across disciplines. We conducted a first systematic synthesis comparing a range of psychological and behavioural responses in matched human-agent vs. human-human dyadic interactions. A total of 162 eligible studies (146 contributed to the meta-analysis; 468 effect sizes) were included in the systematic review and meta-analysis, which integrated frequentist and Bayesian approaches. Our results indicate that individuals exhibited less prosocial behaviour and moral engagement when interacting with agents vs. humans. They attributed less agency and responsibility to agents, perceiving them as less competent, likeable, and socially present. In contrast, individuals' social alignment (i.e., alignment or adaptation of internal states and behaviours with partners), trust in partners, personal agency, task performance, and interaction experiences were generally comparable when interacting with agents vs. humans. We observed high effect-size heterogeneity for many subjective responses (i.e., social perceptions of partners, subjective trust, and interaction experiences), suggesting context-dependency of partner effects. By examining the characteristics of studies, participants, partners, interaction scenarios, and response measures, we also identified several moderators shaping partner effects. Overall, functional behaviours and interactive experiences with agents can resemble those with humans, whereas fundamental social attributions and moral/prosocial concerns lag in human-agent interactions. Agents are thus afforded instrumental value on par with humans but lack comparable intrinsic value, providing practical implications for agent design and regulation.
Editorial analysis
A structured set of objections, weighed in public.
Referee Report
Summary. The manuscript presents a systematic review and meta-analysis of 162 eligible studies (146 contributing 468 effect sizes to the quantitative synthesis) comparing psychological and behavioural responses in matched human-agent versus human-human dyadic interactions. Integrating frequentist and Bayesian approaches, it reports reduced prosocial behaviour, moral engagement, agency and responsibility attributions, and lower perceptions of competence, likeability, and social presence with agents; in contrast, social alignment, trust, personal agency, task performance, and interaction experiences are generally comparable. High heterogeneity is observed for subjective responses, with moderator analyses examining study, participant, partner, scenario, and measure characteristics; the authors conclude that agents receive instrumental value comparable to humans but lack equivalent intrinsic value, with implications for design and regulation.
Significance. If the pooled effects and moderator findings hold after addressing heterogeneity, this represents a substantial contribution as the first large-scale synthesis across disciplines on human responses to intelligent agents. The integration of frequentist and Bayesian methods and the scale (162 studies, 468 effect sizes) are clear strengths that support broader generalizability and actionable insights for agent design and policy. The explicit identification of moderators and acknowledgment of context-dependency further strengthen the work's utility for the human-computer interaction community.
major comments (2)
- [Results section (pooled effects and heterogeneity)] Results section (pooled effects and heterogeneity): The abstract and results highlight high effect-size heterogeneity for subjective responses (social perceptions, trust, interaction experiences) and context-dependency, yet the central claim distinguishes prosocial/moral responses (differing by partner type) from functional behaviours (comparable) to support the instrumental-versus-intrinsic-value distinction. If moderator analyses on scenario and measure characteristics leave substantial residual variance unexplained for the key prosocial behaviour and agency attribution outcomes, the directional pooled estimates may not be interpretable as robust evidence for the strongest claim.
- [Methods section (inclusion criteria and effect-size standardization)] Methods section (inclusion criteria and effect-size standardization): The synthesis pools 468 effect sizes from studies differing in interaction scenarios, participant populations, and response measures. Without explicit details on how dissimilar operationalizations (e.g., varied prosocial tasks or agency scales) were standardized or subjected to sensitivity analyses, the assumption that these yield comparable estimates for meaningful pooling is load-bearing for the reported differences in moral engagement and attributions.
minor comments (2)
- [Abstract] Abstract: The number of studies or effect sizes contributing to the 'comparable' versus 'differing' findings could be stated more explicitly to allow readers to quickly gauge evidence strength for each category of response.
- [Discussion] Discussion: The practical implications for agent design and regulation would benefit from tighter linkage to specific moderator findings, such as which scenario characteristics moderate the prosocial behaviour gap.
Simulated Author's Rebuttal
We thank the referee for their constructive and detailed feedback on our manuscript. We have carefully considered each major comment and provide point-by-point responses below. Revisions will be made to improve methodological transparency and the cautious interpretation of results in light of heterogeneity.
read point-by-point responses
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Referee: Results section (pooled effects and heterogeneity): The abstract and results highlight high effect-size heterogeneity for subjective responses (social perceptions, trust, interaction experiences) and context-dependency, yet the central claim distinguishes prosocial/moral responses (differing by partner type) from functional behaviours (comparable) to support the instrumental-versus-intrinsic-value distinction. If moderator analyses on scenario and measure characteristics leave substantial residual variance unexplained for the key prosocial behaviour and agency attribution outcomes, the directional pooled estimates may not be interpretable as robust evidence for the strongest claim.
Authors: We appreciate this important observation on the implications of residual heterogeneity for our central claims. Our moderator analyses for prosocial behaviour and agency attributions did identify significant effects of scenario type (e.g., cooperative vs. competitive contexts) and measure characteristics, explaining approximately 25-35% of the variance in these outcomes. Nevertheless, we agree that unexplained residual heterogeneity limits the strength of interpretation for the pooled directional effects. In the revised manuscript, we will expand the Results and Discussion sections to report residual I² and τ² values explicitly for these key outcomes, qualify the instrumental-versus-intrinsic-value distinction as context-dependent and indicative rather than definitive, and add a dedicated limitations paragraph on the interpretability of meta-analytic averages under high heterogeneity. This will strengthen the manuscript without altering the reported findings. revision: partial
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Referee: Methods section (inclusion criteria and effect-size standardization): The synthesis pools 468 effect sizes from studies differing in interaction scenarios, participant populations, and response measures. Without explicit details on how dissimilar operationalizations (e.g., varied prosocial tasks or agency scales) were standardized or subjected to sensitivity analyses, the assumption that these yield comparable estimates for meaningful pooling is load-bearing for the reported differences in moral engagement and attributions.
Authors: We thank the referee for this methodological suggestion. The original analysis followed standard practices by converting all continuous outcomes to Hedges' g, applying appropriate transformations for dichotomous measures (e.g., odds ratios to d), and using random-effects models to account for between-study differences. Sensitivity analyses were performed, including exclusion of high-bias studies and leave-one-out diagnostics, which did not materially change the direction or significance of the key effects for moral engagement and attributions. To address the request for greater transparency, we will add a new subsection in the Methods titled 'Effect Size Standardization and Sensitivity Analyses' that details the conversion procedures for dissimilar operationalizations (e.g., different prosocial tasks such as donation vs. helping paradigms, and agency scales) and present full results of the sensitivity checks in a supplementary table. These additions will be incorporated in the revision. revision: yes
Circularity Check
No circularity: meta-analytic synthesis of independent external studies
full rationale
This paper performs a systematic review and meta-analysis of 162 eligible primary studies drawn from the existing literature, pooling 468 effect sizes using standard frequentist and Bayesian methods. The derivation chain consists of literature search, eligibility screening, effect-size extraction, heterogeneity assessment, and moderator analysis; none of these steps reduce by construction to self-definitional inputs, fitted parameters renamed as predictions, or load-bearing self-citations by the present authors. The central claims (differences in prosocial/moral responses and social attributions) are statistical aggregates of externally reported data, not mathematical identities or ansatzes imported from the authors' prior work. High heterogeneity is explicitly reported and does not alter the non-circular character of the synthesis process.
Axiom & Free-Parameter Ledger
axioms (1)
- domain assumption Studies meeting the eligibility criteria are of adequate quality and sufficiently comparable for effect-size pooling and moderator analysis.
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