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PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documents

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arxiv 2303.07240 v1 pith:2CHUESDI submitted 2023-03-13 cs.CV cs.CLcs.LGcs.MM

PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documents

classification cs.CV cs.CLcs.LGcs.MM
keywords biomedicalpmc-oaclassificationdatasetimageimage-captionimage-textmodel
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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Foundation models trained on large-scale dataset gain a recent surge in CV and NLP. In contrast, development in biomedical domain lags far behind due to data scarcity. To address this issue, we build and release PMC-OA, a biomedical dataset with 1.6M image-caption pairs collected from PubMedCentral's OpenAccess subset, which is 8 times larger than before. PMC-OA covers diverse modalities or diseases, with majority of the image-caption samples aligned at finer-grained level, i.e., subfigure and subcaption. While pretraining a CLIP-style model on PMC-OA, our model named PMC-CLIP achieves state-of-the-art results on various downstream tasks, including image-text retrieval on ROCO, MedMNIST image classification, Medical VQA, i.e. +8.1% R@10 on image-text retrieval, +3.9% accuracy on image classification.

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Forward citations

Cited by 8 Pith papers

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score.

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    Contrastive pretraining on mammography atlas image-text pairs improves BI-RADS classification F1 by 1-14% especially in low-label regimes, outperforming equivalent numbers of direct labels in some settings.

  2. REVEAL: Multimodal Vision-Language Alignment of Retinal Morphometry and Clinical Risks for Incident AD and Dementia Prediction

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    REVEAL uses vision-language alignment of retinal morphometry and clinical risk narratives plus group contrastive learning to predict AD and dementia about 8 years early.

  3. REVEAL++: Differentiable Phenotypic Grouping for Vision-Language Retinal Modeling of Alzheimer's Disease Risk

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    REVEAL++ replaces discrete phenotypic groups with differentiable soft multi-positive weighting derived from intra-modality embeddings in contrastive learning, outperforming prior discrete and baseline methods on UK Bi...

  4. BiomedAP: A Vision-Informed Dual-Anchor Framework with Gated Cross-Modal Fusion for Robust Medical Vision-Language Adaptation

    cs.CV 2026-05 unverdicted novelty 5.0

    BiomedAP improves robustness of biomedical VLMs to prompt variations using gated cross-modal fusion and dual-anchor constraints, outperforming baselines on 11 benchmarks.

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    RoiMAM integrates a training-free ROI Generation Module with Semantic Selective Suppression and a Text Prompt Enhancer to produce a compact VLM that reports 2 percent and 4.6 percent accuracy gains on SLAKE and PMC-VQ...

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  8. Data-Centric Foundation Models in Computational Healthcare: A Survey

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