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Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation

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arxiv 2304.12620 v7 pith:PFR62IQD submitted 2023-04-25 cs.CV

Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation

classification cs.CV
keywords medicalsegmentationimagemodeladaptermed-saadaptationanything
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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The Segment Anything Model (SAM) has recently gained popularity in the field of image segmentation due to its impressive capabilities in various segmentation tasks and its prompt-based interface. However, recent studies and individual experiments have shown that SAM underperforms in medical image segmentation, since the lack of the medical specific knowledge. This raises the question of how to enhance SAM's segmentation capability for medical images. In this paper, instead of fine-tuning the SAM model, we propose the Medical SAM Adapter (Med-SA), which incorporates domain-specific medical knowledge into the segmentation model using a light yet effective adaptation technique. In Med-SA, we propose Space-Depth Transpose (SD-Trans) to adapt 2D SAM to 3D medical images and Hyper-Prompting Adapter (HyP-Adpt) to achieve prompt-conditioned adaptation. We conduct comprehensive evaluation experiments on 17 medical image segmentation tasks across various image modalities. Med-SA outperforms several state-of-the-art (SOTA) medical image segmentation methods, while updating only 2\% of the parameters. Our code is released at https://github.com/KidsWithTokens/Medical-SAM-Adapter.

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Forward citations

Cited by 16 Pith papers

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score.

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    cs.CV 2026-04 unverdicted novelty 7.0

    PR-MaGIC refines prompts in in-context segmentation via test-time gradient flow from the mask decoder plus top-1 selection, yielding better masks across benchmarks without training.

  2. Zero-Shot Learning in Industrial Scenarios: New Large-Scale Benchmark, Challenges and Baseline

    cs.AI 2026-06 unverdicted novelty 6.0

    Presents MMIO benchmark and RTVP method achieving state-of-the-art 42.2% AP in zero-shot industrial defect detection.

  3. DeCoDrift: Stabilizing Decoder Coupling in Closed-Loop Foundation Segmentation

    cs.CV 2026-05 unverdicted novelty 6.0

    DeCoDrift stabilizes decoder coupling in closed-loop foundation segmentation by constraining prompt updates without retraining or ground truth.

  4. SAMamba3D: adapting Segment Anything for generalizable 3D segmentation of multiphase pore-scale images

    cs.CV 2026-04 unverdicted novelty 6.0

    SAMamba3D adapts a frozen SAM encoder with Mamba volumetric context and cross-scale features to match or exceed 3D baselines on diverse sandstone and carbonate datasets while reducing case-specific retraining.

  5. Learning to Synergize Semantic and Geometric Priors for Limited-Data Wheat Disease Segmentation

    cs.CV 2026-04 unverdicted novelty 6.0

    SGPer combines DINOv2 semantic priors converted to dense prompts with SAM geometric priors through disease-sensitive adapters and dynamic consistency filtering to deliver robust limited-data wheat disease segmentation.

  6. SegSLR: Promptable Video Segmentation for Isolated Sign Language Recognition

    cs.CV 2025-09 conditional novelty 6.0

    SegSLR uses pose-guided SAM 2 video segmentations to focus RGB streams on the signer's body and hands, improving isolated sign language recognition on ChaLearn249 IsoGD.

  7. COMMA: Coordinate-aware Modulated Mamba Network for 3D Dispersed Vessel Segmentation

    eess.IV 2025-03 unverdicted novelty 6.0

    Presents COMMA, a coordinate-aware Mamba network for 3D vessel segmentation that uses global and local branches, along with a new 570-case labeled dataset.

  8. SAM 2: Segment Anything in Images and Videos

    cs.CV 2024-08 conditional novelty 6.0

    SAM 2 delivers more accurate video segmentation with 3x fewer user interactions and 6x faster image segmentation than the original SAM by training a streaming-memory transformer on the largest video segmentation datas...

  9. Parameter-Efficient Fine-Tuning of Large Pretrained Models for Instance Segmentation Tasks

    cs.CV 2026-06 unverdicted novelty 5.0

    Empirical tests show adapters (2-3 per block) and LoRA on deformable attention achieve competitive instance segmentation with 1-6% parameters tuned versus 40-55% for full fine-tuning.

  10. Anatomy-Anchored Self-Supervision: Distilling Vision Foundation Models for Invariant Ultrasound Representation

    cs.CV 2026-05 unverdicted novelty 5.0

    ANAUS introduces anatomy-anchored self-supervision with LP-SAM delineation and dual policies (inter-view anatomy alignment plus core-region prediction) to distill invariant ultrasound representations, claiming SOTA re...

  11. Any2Any 3D Diffusion Models with Knowledge Transfer: A Radiotherapy Planning Study

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  12. Deep Reprogramming Distillation for Medical Foundation Models

    cs.CV 2026-05 unverdicted novelty 5.0

    DRD introduces a reprogramming module and CKA-based distillation to enable efficient, robust adaptation of medical foundation models to downstream 2D/3D classification and segmentation tasks, outperforming prior PEFT ...

  13. Align then Refine: Text-Guided 3D Prostate Lesion Segmentation

    cs.CV 2026-04 unverdicted novelty 5.0

    A text-guided multi-encoder U-Net with alignment loss, heatmap calibration, and confidence-gated cross-attention refiner sets new state-of-the-art 3D prostate lesion segmentation performance on the PI-CAI dataset.

  14. Towards Any-Quality Image Segmentation via Generative and Adaptive Latent Space Enhancement

    cs.CV 2026-01 unverdicted novelty 5.0

    GleSAM++ improves SAM robustness on degraded images by using generative enhancement, feature alignment, and adaptive degradation prediction while adding few parameters.

  15. Multimodal SAM-adapter for Semantic Segmentation

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    A side-tuning adapter injects RGB-plus-auxiliary-sensor fused features into SAM's encoder, reaching state-of-the-art semantic segmentation on DeLiVER, FMB, and MUSES.

  16. Parameter-Efficient Adaptation of SAM 3 for Automated ITV Generation from 4DCT Images

    eess.IV 2026-06 unverdicted novelty 4.0

    LoRA-adapted SAM 3 with hard-negative mining and phase-coherent filtering achieves median Dice 0.968 on pulmonary structures from 4DCT using seven annotated volumes.